description
In a blinding snowstorm in Buffalo, rookie 49ers running back Isaac Guerendo was not about to let the tough conditions get in his way as he went in search of the end zone. Catching this backwards pass, Guerendo found a lane that his blockers had opened up, and exploited it, scampering through the snow to cross the goal line for the score, the second touchdown of his NFL career. Guerendo tallied 19 yards and one touchdown on four carries in this one, as the 49ers fell to the Bills, 35-10, on Dec. 1, 2024.